Predictive value of pathological and immunohistochemical parameters for axillary lymph node metastasis in breast carcinoma

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Predictive value of pathological and immunohistochemical parameters for axillary lymph node metastasis in breast carcinoma

BACKGROUND/OBJECTIVE While several prognostic factors have been identified in breast carcinoma, the clinical outcome remains hard to predict for individual patients. Better predictive markers are needed to help guide difficult treatment decisions. Axillary lymph node metastasis (ALNM) is one of the most important prognostic determinants in breast carcinoma; however, the reasons why tumors vary ...

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Breast Axillary Lymph Node Metastasis

1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, 3800 Reservoir Road NW, Washington, DC 20007, USA 2Clinical Breast Care Project, 620 Seventh Street, Windber, PA 15963, USA 3Division of Oncogenomics, Department of Pathology, University of Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany 4Department of Pathology, University of Milan School o...

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the clinical value of axillary ultrasonography for detection of axillary lymph node metastasis in cases with breast cancer

background : the axillary lymph node stage is one of the single most important determinants in the prognosis of breast cancer patients. the disadvantages of the two previous methods used for evaluating axillary node metastasis, i.e., axillary lymph node dissection and sentinel lymph node biopsy, have directed researchers to investigate new techniques for this purpose. the aim of the current stu...

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The value of sentinel lymph node biopsy (SLNB) in post-neoadjuvant chemotherapy (NCT) patients is still controversial. We aimed to identify predictors and construct a nomogram for predicting the pathologically complete response (pCR) of axillary lymph nodes (ALNs) after NCT in node positive breast cancer patients. In total, 426 patients with pathologically proven ALN metastasis before NCT were ...

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ژورنال

عنوان ژورنال: Diagnostic Pathology

سال: 2011

ISSN: 1746-1596

DOI: 10.1186/1746-1596-6-18